In the statement Mandela's wife spoke of the love and generosity not only from South Africans, but from around the world.
“The love and generosity has come our way to lighten the burden of anxiety; bringing us love, comfort and hope.” read the statement
She further added that the messages came in the form of all types of communication technology (letters, text messages , email, twitter and the human voice).
She said voices of children in schools or singing outside their home made her feel the closeness of the world.
“Our gratitude is difficult to express but the love and peace we feel give yet more life to the simple 'Thank you!'"
The 94-year-old’s wife was due to appear at a hunger summit in London last week but cancelled to be at her husband’s side.
Meanwhile, Mandela’s ex-wife Winnie Madikizela-Mandel has also been at Madiba’s side since last week at the Pretoria hospital.
Machel also quoted Mandela as saying, "What counts in life is not the mere fact that we have lived. It is what difference we have made in the lives of others."
Mandela is in hospital for a recurring lung infection.
His condition has been described as serious, but stable.